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New Advances in Diabetic Foot Management

New Advances in Diabetic Foot Management

Saeid Kalbasi MD.

Endocrinologist 

Loghman Hospital

October 2012

Technologies

  • Hyperbaric oxygen therapy
  • Negative Pressure wound therapy
  • Growth factors
  • Bioengineered skin substitutes

 

Hyperbaric oxygen therapy

  • Definition, History of Hyperbaric Oxygen therapy
  •  Terminology and Indications and protocols
  • Process of Mediating the Healing of wounds

a.) Collagen synthesis

b.) Angiogenesis

  • Rationale for the Use of Oxygen in wounds
  • Antibacterial actions
  • Reperfusion Injury
  • Topical oxygenation
  • Complications of HBO therapy

 

Definition of HBO Therapy

Involves the inhalation of oxygen at partial pressures meeting or exceeding 1.4 ATA.

---(Whelan,H.T. and Kindwall, E.P. 1999).

  • At its inception,  lacked a scientific basis.
  • Precursors of modern hyperbaric oxygen simply seemed like good ideas.

Henshaw 1662

  • Compressed air therapy resurfaced in the 19th century in the European continent:

a.) Some of the devices could be pressurized to 2 ATA (the pressure equivalent of a 33-foot column of sea water)

b.) Capacity up to 10 occupants.